Invitrogen™ ARGBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546727

Catalog No. PIPA546727

Description

Peptide sequence: LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 100%.

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

Specifications

• Antigen: ARGBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SORBS2
• Gene Alias: 2010203O03Rik; 9430041O17Rik; A530071H08; Arg binding protein 2; Arg/Abl-interacting protein 2; Arg/Abl-interacting protein ArgBP2; arg-binding protein 2; ARGBP2; KIAA0777; leucine-rich repeat extensin-like protein 5; mKIAA0777; nArgBP2; Neural ArgBP2; PRO0618; Sorbin; sorbin and SH3 domain containing 2; sorbin and SH3 domain-containing protein 2; SORBS2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8470
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O94875
• Gene Symbols: SORBS2
• Immunogen: Synthetic peptide directed towards the middle region of human SORBS2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG