Invitrogen™ ARGBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557800

Catalog No. PIPA557800

Description

Immunogen sequence: PRDSPRAISF KNGWQMARQN AEIWSSTEET VSPKIKSRSC DDLLNDDCDS FPDPKVKSES MGSLLCEEDS KESCPMAWGS PYVPEVRSNG RSR Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 84%.

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

Specifications

• Antigen: ARGBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SORBS2
• Gene Alias: 2010203O03Rik; 9430041O17Rik; A530071H08; Arg binding protein 2; Arg/Abl-interacting protein 2; Arg/Abl-interacting protein ArgBP2; arg-binding protein 2; ARGBP2; KIAA0777; leucine-rich repeat extensin-like protein 5; mKIAA0777; nArgBP2; Neural ArgBP2; PRO0618; Sorbin; sorbin and SH3 domain containing 2; sorbin and SH3 domain-containing protein 2; SORBS2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8470
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O94875
• Gene Symbols: SORBS2
• Immunogen: Recombinant protein corresponding to Human ARGBP2. Recombinant protein control fragment (Product #RP-95659).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov