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Invitrogen™ ARGBP2 Polyclonal Antibody
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Catalog No. PIPA557800
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100 μL
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PIPA557800 100 μL
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Catalog No. PIPA557800 Supplier Invitrogen™ Supplier No. PA557800
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PRDSPRAISF KNGWQMARQN AEIWSSTEET VSPKIKSRSC DDLLNDDCDS FPDPKVKSES MGSLLCEEDS KESCPMAWGS PYVPEVRSNG RSR Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 84%.

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARGBP2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SORBS2
Gene Accession No. O94875
Gene Alias 2010203O03Rik; 9430041O17Rik; A530071H08; Arg binding protein 2; Arg/Abl-interacting protein 2; Arg/Abl-interacting protein ArgBP2; arg-binding protein 2; ARGBP2; KIAA0777; leucine-rich repeat extensin-like protein 5; mKIAA0777; nArgBP2; Neural ArgBP2; PRO0618; Sorbin; sorbin and SH3 domain containing 2; sorbin and SH3 domain-containing protein 2; SORBS2
Gene Symbols SORBS2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ARGBP2. Recombinant protein control fragment (Product #RP-95659).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8470
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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