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Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. p-7105983 Shop All R&D Systems Products
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NBP247998A 0.1 mg
NBP247998B 0.2 mg
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Catalog No. NBP247998A Supplier Novus Biologicals Supplier No. NBP2479980.1MG
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Mouse Monoclonal Antibody

Arginase 1/ARG1/liver Arginase Monoclonal specifically detects Arginase 1/ARG1/liver Arginase in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Specifications

Antigen Arginase 1/ARG1/liver Arginase
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone ARG1/1125
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase
Gene Symbols ARG1
Host Species Mouse
Immunogen Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein
Molecular Weight of Antigen 36.5 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism, Myeloid derived Suppressor Cell
Primary or Secondary Primary
Gene ID (Entrez) 383
Test Specificity Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG3 κ
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