Invitrogen™ Arginase 2 Monoclonal Antibody (D3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA541557

Catalog No. PIMA541557

Description

Arginase 2 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Specifications

• Antigen: Arginase 2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P78540
• Gene Symbols: ARG2
• Immunogen: Recombinant protein Arginase II. The antigen corresponds to amino acid range 23-354 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: D3
• Conjugate: Unconjugated
• Gene: ARG2
• Gene Alias: AII; AII type II arginase; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; nonhepatic arginase; non-hepatic arginase; type II arginase
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 384
• Content And Storage: -20°C
• Form: Liquid