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Invitrogen™ Arginase 2 Polyclonal Antibody
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Catalog No. PIPA578820
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100 μg
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Catalog No. Quantity
PIPA578820 100 μg
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Catalog No. PIPA578820 Supplier Invitrogen™ Supplier No. PA578820
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human 293T whole cell, human PC-3 whole cell, human K562 whole cell, human HepG2 whole cell. IHC: human prostate cancer tissue.

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Arginase 2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene ARG2
Gene Accession No. P78540
Gene Alias AII; AII type II arginase; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; nonhepatic arginase; non-hepatic arginase; type II arginase
Gene Symbols ARG2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human Arg2 (67-85aa DFGDLSFTPVPKDDLYNNL).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 384
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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