Invitrogen™ Arginase 2 Recombinant Rabbit Monoclonal Antibody (1Y5U3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542689

Catalog No. PIMA542689

Description

Positive test controls include: 293T. The target is usually found in the following locations: Mitochondrion. Immunogen sequence: FDPTLAPATG TPVVGGLTYR EGMYIAEEIH NTGLLSALDL VEVNPQLATS EEEAKTTANL AVDVIASSFG QTREGGHIVY DQLPTPSSPD ESENQARVRI.

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Specifications

• Antigen: Arginase 2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P78540
• Gene Symbols: ARG2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 255-354 of human Arginase 2 (ARG2) (P78540).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1Y5U3
• Conjugate: Unconjugated
• Gene: ARG2
• Gene Alias: AII; AII type II arginase; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; nonhepatic arginase; non-hepatic arginase; type II arginase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 384
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid