Argonaute 3/e2C3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2301	100 μL

Catalog No. 50-198-2301 Supplier Bioss Supplier No. BS12517R

Description

Rabbit Polyclonal Antibody

AGO3 (protein argonaute-3) is required to RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. AGO3 is proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

Specifications

• Antigen: Argonaute 3/e2C3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: AGO3
• Gene Accession No.: Q9H9G7
• Gene Alias: AGO3; argonaute 3; argonaute 3, RISC catalytic component; Argonaute RISC catalytic component 3; argonaute RISC catalytic subunit 3; Argonaute3; AW048688; BOS_3617; C130014L07Rik; eIF2C 3; eIF-2C 3; EIF2C1; EIF2C3; Eukaryotic translation initiation factor 2C 3; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 3; hAgo3; mAgo3; Piwi/argonaute family protein meIF2C3; Protein argonaute-3
• Gene Symbols: AGO3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 192669
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG