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Invitrogen™ Argonaute 3 Polyclonal Antibody
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Catalog No. PIPA567386
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100 μL
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PIPA567386 100 μL
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Catalog No. PIPA567386 Supplier Invitrogen™ Supplier No. PA567386
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEIGSAGPAGA QPLLMVPRRP GYGTMG Highest antigen sequence identity to the following orthologs - mouse 89%, rat 93%.

AGO3 (protein argonaute-3) is required to RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. AGO3 is proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Argonaute 3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AGO3
Gene Accession No. Q9H9G7
Gene Alias AGO3; argonaute 3; argonaute 3, RISC catalytic component; argonaute RISC catalytic component 3; argonaute RISC catalytic subunit 3; argonaute3; AW048688; C130014L07Rik; eIF2C 3; eIF-2C 3; EIF2C1; EIF2C3; Eukaryotic translation initiation factor 2C 3; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 3; hAgo3; mAgo3; Piwi/Argonaute family protein meIF2C3; Protein argonaute-3
Gene Symbols AGO3
Host Species Rabbit
Immunogen Recombinant Human Argonaut 3. Recombinant protein control fragment (Product #RP-108047).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192669
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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