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Invitrogen™ Argonaute 3 Recombinant Rabbit Monoclonal Antibody (8E0O6)
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Catalog No. PIMA542741
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100 μL
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PIMA542741 100 μL
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Catalog No. PIMA542741 Supplier Invitrogen™ Supplier No. MA542741
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, C2C12, U-87MG, Mouse lung, Mouse brain, Rat lung. Immunogen sequence: RTERVGRSGN IPAGTTVDTD ITHPYEFDFY LCSHAGIQGT SRPSHYHVLW DDNCFTADEL QLLTYQLCHT YVRCTRSVSI PAPAYYAHLV AFRARYHLVD KEHDSAEGSH VSGQSNGRDP QALAKAVQIH QDTLRTMYFA.

AGO3 (protein argonaute-3) is required to RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. AGO3 is proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Argonaute 3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 8E0O6
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AGO3
Gene Accession No. Q8CJF9, Q9H9G7
Gene Alias AGO3; argonaute 3; argonaute 3, RISC catalytic component; argonaute RISC catalytic component 3; argonaute RISC catalytic subunit 3; argonaute3; AW048688; C130014L07Rik; eIF2C 3; eIF-2C 3; EIF2C1; EIF2C3; Eukaryotic translation initiation factor 2C 3; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 3; hAgo3; mAgo3; Piwi/Argonaute family protein meIF2C3; Protein argonaute-3
Gene Symbols AGO3
Host Species Rabbit
Immunogen Recombinant Protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192669, 214150, 313593
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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