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ArgRS/Arginyl tRNA synthetase Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982300
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50-198-2300 100 μL
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Catalog No. 50-198-2300 Supplier Bioss Supplier No. BS12516R
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Description

Rabbit Polyclonal Antibody

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.

Specifications

Antigen ArgRS/Arginyl tRNA synthetase
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RARS1
Gene Accession No. P54136
Gene Alias 2610011N19Rik; 2610037E21Rik; AL033339; arginine tRNA ligase 1, cytoplasmic; Arginine--tRNA ligase, cytoplasmic; Arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; ArgRS; AW985894; DALRD1; HLD9; MGC8641; RARS
Gene Symbols RARS1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ArgRS/Arginyl tRNA syntase.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5917
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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