Invitrogen™ ARHE Polyclonal Antibody

Catalog No.	Quantity
PIPA5106372	100 μL

Catalog No. PIPA5106372 Supplier Invitrogen™ Supplier No. PA5106372

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RND3.

Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras, Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex; GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins; and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form.

Specifications

• Antigen: ARHE
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: RND3
• Gene Accession No.: P61587, P61588, Q6SA80
• Gene Alias: 2610017M01Rik; AI661404; Arhe; memB; MemB protein; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho related protein Rnd3/Rho8; rho8; RHOE; rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rnd3; small GTP binding protein Rho8
• Gene Symbols: RND3
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human RND3(Accession P61587), corresponding to amino acid residues S178-A228.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 295588, 390, 74194
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov