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Invitrogen™ ARHGAP22 Polyclonal Antibody
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Catalog No. PIPA595800
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100 μL
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PIPA595800 100 μL
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Catalog No. PIPA595800 Supplier Invitrogen™ Supplier No. PA595800
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NVPAPGLVPG IPSVASMAWS GASSSESSVG GSLSSCTACR ASDSSARSSL HTDWALEPSP LPSSSEDPKS LDLDHSMDEA GAGASNSEPS EPDSPTREHA RRSEALQGLV TELRAELCRQ RTEYERSVKR IEEGSADLRK R; Positive Samples: Mouse kidney, Mouse lung, Rat kidney, Rat lung; Cellular Location: Cytoplasm, Nucleus.

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGAP22
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Arhgap22
Gene Accession No. Q8BL80
Gene Alias Arhgap22; B230341L19Rik; p68RacGAP; RHG22; Rho GTPase activating protein 22; rho GTPase-activating protein 22; RHOGAP2; RhoGap22; Rho-type GTPase-activating protein 22
Gene Symbols Arhgap22
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human ARHGAP22 (NP_0012429531).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 239027, 306279
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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