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Invitrogen™ ARHGAP22 Polyclonal Antibody
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Catalog No. PIPA536510
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100 μL
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Catalog No. Quantity
PIPA536510 100 μL
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Catalog No. PIPA536510 Supplier Invitrogen™ Supplier No. PA536510
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 77 kDa. Purity is >95% by SDS-PAGE.

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGAP22
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.2
Gene Arhgap22
Gene Accession No. Q7Z5H3, Q8BL80
Gene Alias Arhgap22; B230341L19Rik; p68RacGAP; RHG22; Rho GTPase activating protein 22; rho GTPase-activating protein 22; RHOGAP2; RhoGap22; Rho-type GTPase-activating protein 22
Gene Symbols Arhgap22
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 564-620 of human ARHGAP22.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 239027, 306279, 58504
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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