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Invitrogen™ ARHGAP24 Polyclonal Antibody
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Catalog No. PIPA5104104
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PIPA5104104 100 μL
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Catalog No. PIPA5104104 Supplier Invitrogen™ Supplier No. PA5104104
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RHG24.

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGAP24
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ARHGAP24
Gene Accession No. Q5U2Z7, Q8C4V1, Q8N264
Gene Alias 0610025G21Rik; Arhgap24; Down-regulated in nephrectomized rat kidney #2; DR-NR#2; Filamin-A-associated RhoGAP; FILGAP; p73; p73RhoGAP; RAC1- and CDC42-specific GTPase-activating protein of 72 kDa; RCGAP72; RC-GAP72; Rho GTPase activating protein 24; rho GTPase-activating protein 24; rhoGAP of 73 kDa; Rho-type GTPase-activating protein 24; Sarcoma antigen NY-SAR-88; si:ch211-65i12.2
Gene Symbols ARHGAP24
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARHGAP24(Accession Q8N264), corresponding to amino acid residues S573-A623.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 231532, 305156, 83478
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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