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ARHGDIB/D4-GDI/RhoGDI2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501568753
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50-156-8753 100 μL
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Catalog No. 50-156-8753 Supplier Bethyl Laboratories, Inc Supplier No. A304815A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).

Specifications

Antigen ARHGDIB/D4-GDI/RhoGDI2
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ARHGDIB
Gene Accession No. P52566
Gene Alias D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2
Gene Symbols ARHGDIB
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 397
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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