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Invitrogen™ ARHGDIG Polyclonal Antibody
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Catalog No. PIPA519354
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100 μg
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Catalog No. Quantity
PIPA519354 100 μg
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Catalog No. PIPA519354 Supplier Invitrogen™ Supplier No. PA519354
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDIalpha, Ly-GDI (also known as Rho GDIbeta and previously known as GDI/D4) and Rho GDIgamma. The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGDIG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene ARHGDIG
Gene Accession No. Q99819
Gene Alias Arhgdig; Gdi5; guanosine diphosphate (GDP) dissociation inhibitor 5, Rho associated; rho GDI 3; Rho GDIgamma; Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP dissociation inhibitor gamma; rho GDP-dissociation inhibitor 3; RhoGDI gamma; Rho-GDI gamma; Rho-GDI2; Rho-GDI-3; RHOGDI-3; Rho-GDIgamma; RIP2
Gene Symbols ARHGDIG
Host Species Goat
Immunogen Synthetic peptide sequence (EAVPEYRAPGRK) corresponding to the C-terminus amino acids of ARHGDIG (aa 43-55).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 398
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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