Invitrogen™ ARHGEF12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143957

Catalog No. PIPA5143957

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HEL whole cell, human K562 whole cell, rat brain tissue. Flow: HL-60 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ARHGEF12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGEF12
• Gene Alias: 2310014B11Rik; Arhgef12; AU019857; KIAA0382; LARG; leukemia-associated Rho guanine nucleotide exchange factor; leukemia-associated Rho guanine-nucleotide exchange factor; leukemia-associated RhoGEF; mKIAA0382; PRO2792; Rho guanine nucleotide exchange factor (GEF) 12; Rho guanine nucleotide exchange factor 12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23365, 367072
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q9NZN5
• Gene Symbols: ARHGEF12
• Immunogen: E.coli-derived human LARG/ARHGEF12 recombinant protein (Position: T4-S254).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG