Invitrogen™ ARHGEF12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101847

Catalog No. PIPA5101847

Description

Antibody detects endogenous levels of total ARHGEF12.

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ARHGEF12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGEF12
• Gene Alias: 2310014B11Rik; Arhgef12; AU019857; KIAA0382; LARG; leukemia-associated Rho guanine nucleotide exchange factor; leukemia-associated Rho guanine-nucleotide exchange factor; leukemia-associated RhoGEF; mKIAA0382; PRO2792; Rho guanine nucleotide exchange factor (GEF) 12; Rho guanine nucleotide exchange factor 12
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23365, 367072, 69632
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8R4H2, Q9NZN5
• Gene Symbols: ARHGEF12
• Immunogen: A synthesized peptide derived from human ARHGEF12(Accession Q9NZN5), corresponding to amino acid residues K583-P633.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov