Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA552498

Invitrogen™ ARHGEF17 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA552498
missing translation for 'changeView'
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA552498 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 missing translation for 'options'
Catalog No. PIPA552498 Supplier Invitrogen™ missing translation for 'supplierNo' PA552498
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VYQREAGHFW DPQNFKSVTL GTQGSPITKM VSVGGRLWCG CQNRVLVLSP DTLQLEHMFY VGQDSSRCVA CMVDSSLGVW VTLKGSAHVC LYHPDTFEQL AEVDVTPPVH RMLAGSDAII RQHKAACLRI TALLVCEELL W Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGEF17
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ARHGEF17
Gene Accession No. Q96PE2
Gene Alias 164 kDa Rho-specific guanine-nucleotide exchange factor; 8030463K16; AI428794; Arhgef17; AW558066; BC035332; Kiaa0337; mKIAA0337; P164RHOGEF; p164-RhoGEF; Rho guanine nucleotide exchange factor (GEF) 17; Rho guanine nucleotide exchange factor 17; Rho-specific guanine-nucleotide exchange factor 164 kDa; TEM4; Tumor endothelial marker 4
Gene Symbols ARHGEF17
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ARHGEF17. Recombinant protein control fragment (Product #RP-100948).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9828
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.