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Invitrogen™ ARHGEF17 Polyclonal Antibody
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Catalog No. PIPA5103351
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Quantity:
100 μL
Catalog No. Quantity
PIPA5103351 100 μL
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Catalog No. PIPA5103351

Supplier: Invitrogen™ PA5103351

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ARHGEF17.

Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGEF17
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ARHGEF17
Gene Accession No. Q80U35, Q96PE2
Gene Alias 164 kDa Rho-specific guanine-nucleotide exchange factor; 8030463K16; AI428794; Arhgef17; AW558066; BC035332; Kiaa0337; mKIAA0337; P164RHOGEF; p164-RhoGEF; Rho guanine nucleotide exchange factor (GEF) 17; Rho guanine nucleotide exchange factor 17; Rho-specific guanine-nucleotide exchange factor 164 kDa; TEM4; Tumor endothelial marker 4
Gene Symbols ARHGEF17
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARHGEF17(Accession Q96PE2), corresponding to amino acid residues T1679-L1729.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 207212, 9828
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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