Invitrogen™ ARHGEF18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119935

Catalog No. PIPA5119935

Description

Positive Control: HepG2 cell lysate, Hela cell lysate, 293 cell lysate, PC-3 cell lysate, Daudi cell lysate, rat kidney tissue, Hela. Subcellular Location: Cytoskeleton, Cell membrane, Apical cell membrane, Cytoplasm.

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: ARHGEF18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Arhgef18
• Gene Alias: 114 kDa Rho-specific guanine nucleotide exchange factor; AI467246; Arhgef18; D030053O22Rik; KIAA0521; p114RhoGEF; P114-RhoGEF; p114-Rho-GEF; rho guanine nucleotide exchange factor 18; rho/rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; Rho-specific guanine nucleotide exchange factor p114; SA-RhoGEF; Septin-associated RhoGEF
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23370, 304193
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q6ZSZ5
• Gene Symbols: Arhgef18
• Immunogen: Recombinant protein within human p114RhoGEF aa 1000-1200/1361.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG