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Invitrogen™ ARHGEF18 Polyclonal Antibody
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Catalog No. PIPA5119935
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100 μL
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PIPA5119935 100 μL
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Catalog No. PIPA5119935 Supplier Invitrogen™ Supplier No. PA5119935
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Description

Rabbit Polyclonal Antibody

Positive Control: HepG2 cell lysate, Hela cell lysate, 293 cell lysate, PC-3 cell lysate, Daudi cell lysate, rat kidney tissue, Hela. Subcellular Location: Cytoskeleton, Cell membrane, Apical cell membrane, Cytoplasm.

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGEF18
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Arhgef18
Gene Accession No. Q6ZSZ5
Gene Alias 114 kDa Rho-specific guanine nucleotide exchange factor; AI467246; Arhgef18; D030053O22Rik; KIAA0521; p114RhoGEF; P114-RhoGEF; p114-Rho-GEF; rho guanine nucleotide exchange factor 18; rho/rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; Rho-specific guanine nucleotide exchange factor p114; SA-RhoGEF; Septin-associated RhoGEF
Gene Symbols Arhgef18
Host Species Rabbit
Immunogen Recombinant protein within human p114RhoGEF aa 1000-1200/1361.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23370, 304193
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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