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Invitrogen™ ARHGEF4 Monoclonal Antibody (ARHGEF-08), PE
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Catalog No. PIMA528621
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100 μg
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PIMA528621 100 μg
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Catalog No. PIMA528621 Supplier Invitrogen™ Supplier No. MA528621
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Mouse Monoclonal Antibody

This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain.

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGEF4
Applications Flow Cytometry
Classification Monoclonal
Clone ARHGEF-08
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Arhgef4
Gene Accession No. Q9NR80
Gene Alias 9330140K16Rik; APC-stimulated guanine nucleotide exchange factor; APC-stimulated guanine nucleotide exchange factor 1; Arhgef4; Asef; ASEF1; DKFZp434G2016; ENSMUSG00000070955; GEF4; Kiaa1112; LOC100067370; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 4; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4; STM6
Gene Symbols Arhgef4
Host Species Mouse
Immunogen Recombinant fragment of human ARHGEF4 (amino acids 143-271).
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50649
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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