Invitrogen™ ARHGEF4 Monoclonal Antibody (ARHGEF-08)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528622

Catalog No. PIMA528622

Description

This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain.

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.

Specifications

• Antigen: ARHGEF4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: Q9NR80
• Gene Symbols: Arhgef4
• Immunogen: Recombinant fragment of human ARHGEF4 (amino acids 143-271).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: ARHGEF-08
• Conjugate: Unconjugated
• Gene: Arhgef4
• Gene Alias: 9330140K16Rik; APC-stimulated guanine nucleotide exchange factor; APC-stimulated guanine nucleotide exchange factor 1; Arhgef4; Asef; ASEF1; DKFZp434G2016; ENSMUSG00000070955; GEF4; Kiaa1112; LOC100067370; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 4; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4; STM6
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 50649
• Content And Storage: 4°C, do not freeze
• Form: Liquid