Invitrogen™ ARID4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA132488

Catalog No. PIPA132488

Description

Recommended positive controls: HepG2. Predicted reactivity: Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93%.

ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.

Specifications

• Antigen: ARID4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARID4A
• Gene Alias: A630009N03; A630067N03Rik; ARID domain-containing protein 4A; ARID4A; AT rich interactive domain 4A (Rbp1 like); AT rich interactive domain 4A (RBP1-like); AT-rich interaction domain 4A; AT-rich interactive domain-containing protein 4A; MmRBBP1; Rbbp1; RBBP-1; RBP1; RBP-1; retinoblastoma binding protein 1; retinoblastoma-binding protein 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5926
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P29374
• Gene Symbols: ARID4A
• Immunogen: Synthetic peptide derived from a region between residues 1119 - 1168 of human Retinoblastoma binding protein 1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov