ARMER Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8401	Proteintech Group Inc 129881AP150UL	150 μL

Description

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Specifications

• Antigen: ARMER
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q15041, Q9JKW0
• Gene ID (Entrez): 23204, 293551, 54208
• Immunogen: ARMER Fusion Protein Ag3639
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ARL6IP1

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Aip 1, AIP1, ARL 6 interacting protein 1, ARL6IP, ARL6IP1, ARMER, KIAA0069
• Gene Symbols: Arl6ip1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody