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Invitrogen™ ARMET Monoclonal Antibody (C2), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA543947
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Description
The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Specifications
ARMET | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P55145 | |
MANF | |
Gly28-Leu182 (Accession P55145), with N-terminal His Tag. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
Immunohistochemistry (Paraffin), Western Blot | |
C2 | |
Unconjugated | |
MANF | |
3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET | |
Mouse | |
Protein A/G | |
RUO | |
7873 | |
-20°C | |
Liquid |
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