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Invitrogen™ ARMET Polyclonal Antibody
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Catalog No. PIPA596542
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100 μL
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PIPA596542 100 μL
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Catalog No. PIPA596542 Supplier Invitrogen™ Supplier No. PA596542
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL Positive Samples: U-251MG, MCF7, PC-3.

The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARMET
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene MANF
Gene Accession No. P0C5H9, P55145, Q9CXI5
Gene Alias 3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET
Gene Symbols MANF
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315989, 74840, 7873
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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