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Invitrogen™ ARMET Polyclonal Antibody
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Catalog No. PIPA589198
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100 μL
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PIPA589198 100 μL
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Catalog No. PIPA589198 Supplier Invitrogen™ Supplier No. PA589198
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SRALRPGDCE VCISYLGRFY QDLKDRDVTF SPATIENELI KFCREARGKE NRLCYYIGAT DDAATKIINE VSKPLAHHIP VEKICEKLKK KDSQICELKY DKQIDLSTVD LKKLRVKELK KILDDWGETC KGCAEKSDYI RKINELMPKY APKAASAR; Positive Samples: Jurkat, U251, MCF7.

The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARMET
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.84 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MANF
Gene Accession No. P0C5H9, P55145, Q9CXI5
Gene Alias 3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET
Gene Symbols MANF
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human ARMET/ARP/MANF (NP_0060014).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315989, 74840, 7873
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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