Invitrogen™ ARMET Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589198

Catalog No. PIPA589198

Description

Immunogen sequence: SRALRPGDCE VCISYLGRFY QDLKDRDVTF SPATIENELI KFCREARGKE NRLCYYIGAT DDAATKIINE VSKPLAHHIP VEKICEKLKK KDSQICELKY DKQIDLSTVD LKKLRVKELK KILDDWGETC KGCAEKSDYI RKINELMPKY APKAASAR; Positive Samples: Jurkat, U251, MCF7.

The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

Specifications

• Antigen: ARMET
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MANF
• Gene Alias: 3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 315989, 74840, 7873
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.84 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P0C5H9, P55145, Q9CXI5
• Gene Symbols: MANF
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human ARMET/ARP/MANF (NP_0060014).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov