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Tocris Bioscience™ ARN 11391
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Catalog No. 790910
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79-091-0 10 mg
79-095-0 50 mg
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Description

Potentiator of the IP3-gated calcium channel ITPR1

ARN 11391 is a potentiator of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1). It amplifies intracellular calcium ion signaling by acting directly on ITPR1. ARN 11391 also potentiates calcium signaling in cells expressing mutant ITPR1 which is associated with SCA29, a form of spinocerebellar ataxia.

Specifications

Chemical Name or Material 2-Ethyl-4,5,6,7-tetrahydro-N-[2-[(tetrahydro-2 H-pyran-2-yl)methoxy]phenyl]-2 H-indazole-3-carboxamide
CAS 1214569-31-9
Quantity 10 mg
Target IP3R1
Molecular Formula C22H29N3O3
Purity 0.98
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