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Invitrogen™ ARNT2 Polyclonal Antibody
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Catalog No. PIPA5101263
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100 μL
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PIPA5101263 100 μL
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Catalog No. PIPA5101263 Supplier Invitrogen™ Supplier No. PA5101263
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ARNT2.

AhR, ARNT1, ARNT2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common PAS motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator proteins (Arnt 1 or Arnt 2) are required for ligand-dependent nuclear translocation of the Ah receptor and are also necessary for Ah receptor binding to the XRE element. BMAL1 (Brain and Muscle Arnt-like protein 1), also designated Arnt 3, TIC, JAP3 or MOP-3, has been shown to dimerize with Clock and bind to the promoter region of mPer1, suggesting that this protein plays a role in regulation of circadian oscillation in mammals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARNT2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Arnt2
Gene Accession No. Q61324, Q78E60, Q9HBZ2
Gene Alias Ah receptor nuclear translocator; Arnt; ARNT 2; ARNT protein 2; Arnt2; arnt2a; ARNT2b; ARNT2c; arnt2X; Aryl hydrocarbon receptor nuclear translocator 2; aryl hydrocarbon receptor nuclear translocator 2A; aryl hydrocarbon receptor nuclear translocator type 2a; aryl hydrocarbon receptor nuclear translocator type 2b; aryl hydrocarbon receptor nuclear translocator type 2c; aryl-hydrocarbon receptor nuclear translocator 2; bHLHe1; bHLH-PAS factor ARNT2B; chunp6921; Class E basic helix-loop-helix protein 1; Hif-2b; KIAA0307; mKIAA0307; unm t30256; unm_t30256; WEDAS; zfARNT2; zfARNT2a; zfARNT2b; zfARNT2c
Gene Symbols Arnt2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARNT2(Accession Q9HBZ2), corresponding to amino acid residues T30-T80.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11864, 25243, 9915
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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