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Invitrogen™ Arp2 Polyclonal Antibody
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Catalog No. PIPA5143649
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PIPA5143649 100 μL
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Catalog No. PIPA5143649 Supplier Invitrogen™ Supplier No. PA5143649
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Description

Rabbit Polyclonal Antibody

The antibody detects 44 and 32 kDa* proteins corresponding to the molecular mass of Arp2 on SDS-PAGE immunoblots of human A431, HUVEC, HeLa, and Jurkat cells as well as rat PC12, mouse C2C12, and rabbit fibroblasts.

ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Arp2
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene ACTR2
Gene Accession No. P61160, P61161, Q5M7U6
Gene Alias 4921510D23Rik; AA409782; Actin-like protein 14D; Actin-like protein 2; Actin-related protein 14 Da; Actin-related protein 14D; Actin-related protein 2; Actr14D; Actr2; Arp14D; ARP2; ARP2 actin related protein 2 homolog; ARP2 actin-related protein 2; ARP2 actin-related protein 2 homolog; ARP2 actin-related protein 2 homolog (yeast); Arp2-PA; Arp2-PB; Arp2-PC; CG9901; CG9901-PA; CG9901-PB; CG9901-PC; D6Ertd746e; Dmel\CG9901; Dmel_CG9901; I79_003843; LD18955p
Gene Symbols ACTR2
Host Species Rabbit
Immunogen Arp2 (C-terminal region) synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human Arp2. This peptide sequence is highly conserved in rat, mouse, chicken, and frog Arp2 proteins.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10097, 289820, 66713
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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