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Invitrogen™ ARRDC3 Polyclonal Antibody
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Catalog No. PIPA5109414
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100 μL
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PIPA5109414 100 μL
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Catalog No. PIPA5109414 Supplier Invitrogen™ Supplier No. PA5109414
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Rabbit Polyclonal Antibody

Immunogen sequence: MVLGKVKSLT ISFDCLNDSN VPVYSSGDTV SGRVNLEVTG EIRVKSLKIH ARGHAKVRWT ESRNAGSNTA YTQNYTEEVE YFNHKDILIG HERDDDNSEE GFHTIHSGRH EYAFSFELPQ TPLATSFEGR HGSVRYWVKA ELHRPWLLPV KLKKEFTVFE HIDINTPSLL SPQAGTKEKT LCCWFCTSGP ISLSAKIERK GYTPGESIQI FAEIENCSSR MVVPKAAIYQ TQAFYAKGKM KEVKQLVANL RGESLSSGKT ETWNGKLLKI.

Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARRDC3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.73 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ARRDC3
Gene Accession No. Q6TXF1
Gene Alias AI450344; alpha-arrestin 3; ARRDC3; arrestin domain containing 3; arrestin domain-containing protein 3; Kiaa1376; Liver regeneration-related protein LRRG00048; LRRGT00048; mKIAA1376; TBP-2-like inducible membrane protein; thioredoxin-binding protein-2-like inducible membrane; TLIMP
Gene Symbols ARRDC3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ARRDC3 (NP_065852.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 309945
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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