Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ ARS2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA560148
Description
Immunogen sequence: TCSLFMRNIA PNISRAEIIS LCKRYPGFMR VALSEPQPER RFFRRGWVTF DRSVNIKEIC WNLQNIRLRE CELSPGVNRD LTRRVRNING ITQHKQI Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 43%.
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription. [UniProt].
Specifications
ARS2 | |
Polyclonal | |
Unconjugated | |
SRRT | |
2810019G02Rik; Ars2; arsenate resistance protein 2; arsenate resistance protein ARS2; arsenite resistance protein; arsenite resistance protein 2; arsenite-resistance protein 2; Asr2; ASR2A; ASR2B; ASR2C; ASR2D; ch211-283g2.4; CHUNP6881; LOC686980; serrate; Serrate RNA effector molecule homolog; serrate RNA effector molecule homolog (Arabidopsis); serrate, RNA effector molecule; similar to arsenate resistance protein 2; srrt; zgc:92060 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
51593 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9BXP5 | |
SRRT | |
Recombinant protein corresponding to Human ARS2. Recombinant protein control fragment (Product #RP-92626). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction