ARSG Mouse anti-Human, Clone: OTI2A8, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-1008	100 μg

Catalog No. 50-167-1008 Supplier OriGene Supplier No. CF812731

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

Specifications

• Antigen: ARSG
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2A8
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: ARSG
• Gene Accession No.: Q96EG1
• Gene Alias: arylsulfatase G
• Gene Symbols: ARSG
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 17-525 of human ARSG produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22901
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1