ARSG Mouse anti-Human, Clone: OTI4H3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF812732

Catalog No. 50-167-1009

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

Specifications

• Antigen: ARSG
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ARSG
• Gene Alias: arylsulfatase G
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22901
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI4H3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q96EG1
• Gene Symbols: ARSG
• Immunogen: Human recombit protein fragment corresponding to amino acids 17-525 of human ARSG produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a