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Invitrogen™ Artemin Polyclonal Antibody
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Catalog No. PIPA596876
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100 μL
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PIPA596876 100 μL
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Catalog No. PIPA596876 Supplier Invitrogen™ Supplier No. PA596876
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Description

Rabbit Polyclonal Antibody

Positive Samples: 22Rv1 Immunogen sequence: GCRLRSQLVP VRALGLGHRS DELVRFRFCS GSCRRARSPH DLSLASLLGA GALRPPPGSR PVSQPCCRPT RYEAVSFMDV NSTWRTVDRL SATACGCLG.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Artemin
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.62 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene ARTN
Gene Accession No. Q5T4W7, Q6AYE8, Q9Z0L2
Gene Alias Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
Gene Symbols ARTN
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 122-220 of human ARTN (NP_4764322).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11876, 362572, 9048
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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