Invitrogen™ Artemin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596876

Catalog No. PIPA596876

Description

Positive Samples: 22Rv1 Immunogen sequence: GCRLRSQLVP VRALGLGHRS DELVRFRFCS GSCRRARSPH DLSLASLLGA GALRPPPGSR PVSQPCCRPT RYEAVSFMDV NSTWRTVDRL SATACGCLG.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Artemin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARTN
• Gene Alias: Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11876, 362572, 9048
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.62 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q5T4W7, Q6AYE8, Q9Z0L2
• Gene Symbols: ARTN
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 122-220 of human ARTN (NP_4764322).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG