Invitrogen™ Artemin Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142605

Catalog No. PIPA5142605

Description

Additional Information: This antibody is expected to recognize all reported isoforms (NP_003967.2; NP_476501.1; NP_476431.2). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Artemin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARTN
• Gene Alias: Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 9048
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5T4W7
• Gene Symbols: ARTN
• Immunogen: Peptide with sequence C-NSTWRTVDRLS.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov