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Invitrogen™ Artemin Polyclonal Antibody
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Catalog No. PIPA547063
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100 μg
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PIPA547063 100 μg
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Catalog No. PIPA547063 Supplier Invitrogen™ Supplier No. PA547063
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Description

Goat Polyclonal Antibody

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) GDNF, recombinant rat GDNF, rhNeurturin, and rhTGF-beta 1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Artemin
Applications Immunohistochemistry, Neutralization, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene ARTN
Gene Accession No. Q9Z0L2
Gene Alias Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
Gene Symbols ARTN
Host Species Goat
Immunogen E. coli-derived recombinant mouse Artemin Ala112-Gly224.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11876
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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