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Invitrogen™ Artemin Polyclonal Antibody
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Catalog No. APPA6738
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100 μg
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Catalog No. Quantity
APPA6738 100 μg
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Catalog No. APPA6738 Supplier Invitrogen™ Supplier No. PA116738
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Description

Rabbit Polyclonal Antibody

Suggested positive control: human dorsal root ganglia/CNS preparation.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Artemin
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ARTN
Gene Accession No. Q5T4W7
Gene Alias Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
Gene Symbols ARTN
Host Species Rabbit
Immunogen Amino acids GPGSRARAAGARGC of human Artemin (aa 110-123).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9048
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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