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Invitrogen™ Arylsulfatase G Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547640

Catalog No. PIPA547640


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Description

Description

In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant mouse ARSA, recombinant human (rh) ARSB and rhARSJ is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Arylsulfatase G
Polyclonal
Unconjugated
ARSG
6330406P08Rik; AI846872; Arsg; Arylsulfatase G; ASG; KIAA1001; RGD1306571; UNQ839/PRO1777
Sheep
Antigen Affinity Chromatography
RUO
74008
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunoprecipitation, Western Blot
0.2 mg/mL
PBS with 5% trehalose and No Preservative
Q3TYD4
ARSG
CHO-derived recombinant mouse Arylsulfatase G/ARSG Gly17-Val525.
100 μg
Primary
Mouse
Antibody
IgG
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