Invitrogen™ Arylsulfatase G Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547640

Catalog No. PIPA547640

Description

In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant mouse ARSA, recombinant human (rh) ARSB and rhARSJ is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

Specifications

• Antigen: Arylsulfatase G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARSG
• Gene Alias: 6330406P08Rik; AI846872; Arsg; Arylsulfatase G; ASG; KIAA1001; RGD1306571; UNQ839/PRO1777
• Host Species: Sheep
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 74008
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q3TYD4
• Gene Symbols: ARSG
• Immunogen: CHO-derived recombinant mouse Arylsulfatase G/ARSG Gly17-Val525.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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