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Invitrogen™ Arylsulfatase G Polyclonal Antibody
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Catalog No. PIPA5101437
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100 μL
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PIPA5101437 100 μL
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Catalog No. PIPA5101437 Supplier Invitrogen™ Supplier No. PA5101437
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ARSG.

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Arylsulfatase G
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ARSG
Gene Accession No. Q32KJ9, Q3TYD4, Q96EG1
Gene Alias 6330406P08Rik; AI846872; Arsg; Arylsulfatase G; ASG; KIAA1001; RGD1306571; UNQ839/PRO1777
Gene Symbols ARSG
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARSG(Accession Q96EG1), corresponding to amino acid residues P260-C310.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22901, 303631, 74008
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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