Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA524224

Invitrogen™ ASAHL Monoclonal Antibody (511702)
GREENER_CHOICE

Catalog No. PIMA524224
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA524224 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA524224 Supplier Invitrogen™ Supplier No. MA524224
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

In direct ELISAs, 100% cross-reactivity with recombinant mouse ASAHL is observed and no cross-reactivity with recombinant human ASAH2 or recombinant mouse ASAH2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

N-acylsphingosine amidohydrolase-like 1 (ASAHL), commonly referred to as acid ceramidase-like protein, is a gene located on human chromosome 22q13.31. ASAHL encodes a protein that functions as a ceramidase, responsible for hydrolyzing ceramide into sphingosine and fatty acid, which are pivotal for cell signaling pathways that regulate cell growth, differentiation, and apoptosis. Though similar to acid ceramidase, ASAHL's specific biological role and tissue distribution remain active research areas, suggesting potential involvement in lipid metabolism and cellular homeostasis. Dysregulation of ceramidase activity, including ASAHL, is linked to various diseases, such as cancer, neurodegenerative disorders, and metabolic syndromes, due to the crucial role of sphingolipid signaling in these conditions. The gene's activity may influence ceramide levels within cells, impacting susceptibility to apoptosis and other cell fate decisions, highlighting its importance in pathophysiological contexts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASAHL
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 511702
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Naaa
Gene Accession No. Q02083
Gene Alias 2210023K21Rik; 3830414F09Rik; acid ceramidase-like protein; Asahl; ASAH-like protein; LOW QUALITY PROTEIN: N-acylethanolamine-hydrolyzing acid amidase; Naaa; N-acylethanolamine acid amidase; N-acylethanolamine-hydrolyzing acid amidase; N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta; N-acylsphingosine amidohydrolase-like; PLT
Gene Symbols Naaa
Host Species Mouse
Immunogen CHO-derived recombinant human ASAHL/N-acylethanolamine-hydrolyzing Acid A isoform 1 Ser29-Lys359 (Val151Ile).
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27163
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.