Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. ASAP2 Polyclonal Antibody, Bethyl Laboratories 

ASAP2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564812
Encompass_Preferred
Change view
Click to view available options
Quantity:
20 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-156-4812 20 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-156-4812 Supplier Bethyl Laboratories, Inc Supplier No. A303311AT
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

ASAP2 is a multidomain protein belonging to the beta family with two ANK repeats, an Arf-GAP domain, a PH domain and a SH3 domain. This protein localizes in the Golgi apparatus and also at the plasma membrane where it colocalizes with protein tyrosine kinase 2-beta (PYK2) and forms a stable complex with PYK2 in vivo. ASAP2 is tyrosine phosphorylated by activated PYK2. It functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. ASAP2 activates the small GTPases ARF1, ARF5 and ARF6 and regulates the formation of post-Golgi vesicles and modulates constitutive secretion. It modulates phagocytosis mediated by Fc gamma receptor and ARF6. Usually detected in heart, brain, placenta, kidney, monocytes and pancreas, it is up-regulated during monocyte maturation. Multiple transcript variants encoding different isoforms have been found.

Specifications

Antigen ASAP2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ASAP2
Gene Accession No. O43150
Gene Alias AMAP2, centaurin, beta 3, CENTB3, DDEF2, development and differentiation enhancing factor 2, development and differentiation-enhancing factor 2, KIAA0400, PAG3, PAP, Pap-alpha, paxillin-associated protein with ARF GAP activity 3, PYK2 C terminus-associated protein, pyk2 C-terminus-associated protein, SHAG1
Gene Symbols ASAP2
Host Species Rabbit
Immunogen Between 900 and 950
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8853
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.