Invitrogen™ ASB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550361

Catalog No. PA550361

Description

The antibody detects endogenous levels of total ASB2 protein.

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Specifications

• Antigen: ASB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASB2
• Gene Alias: 1110008E15Rik; ankyrin repeat and SOCS box containing 2; ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box-containing 2; ankyrin repeat and SOCS box-containing protein 2; ankyrin repeat and SOCS box-containing protein 2a; ankyrin repeat-containing SOCS box protein 2; Asb2; ASB-2; asb2 {ECO:0000312; EMBL:AAH85882.1}; MGC40044
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51676
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 2.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q96Q27
• Gene Symbols: ASB2
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human ankyrin repeat and SOCS box containing 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG