ASC2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300410A

Catalog No. 50-155-7560

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Specifications

• Antigen: ASC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCOA6
• Gene Alias: activating signal cointegrator 2, activating signal cointegrator-2, AIB3, amplified in breast cancer protein 3, amplified in breast cancer-3 protein, ASC2, ASC-2, cancer-amplified transcriptional coactivator ASC-2, KIAA0181, NRC, NRC RAP250, nuclear receptor coactivator RAP250, nuclear receptor-activating protein, 250 kDa, peroxisome proliferator-activated receptor interacting protein, peroxisome proliferator-activated receptor-interacting protein, PPAR-interacting protein, PRIP, RAP250, thyroid hormone receptor binding protein, thyroid hormone receptor-binding protein, TRBP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23054
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q14686
• Gene Symbols: NCOA6
• Immunogen: Between 1050 and 1100
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG