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ASCC1 Monoclonal Antibody (OTI2D7), TrueMAB™, OriGene
SDP

Catalog No. 501674508
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100 μL
30 μL
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50-167-4508 100 μL
50-254-0771 30 μL
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Catalog No. 50-167-4508 Supplier OriGene Supplier No. TA503668
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Mouse Monoclonal Antibody

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Specifications

Antigen ASCC1
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI2D7
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ASCC1
Gene Accession No. Q8N9N2
Gene Alias ASC1p50, CGI-18, SMABF2, p50
Gene Symbols ASCC1
Host Species Mouse
Immunogen Full length human recombit protein of human ASCC1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51008
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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