Invitrogen™ ASCC1 Monoclonal Antibody (OTI6G5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525727

Catalog No. PIMA525727

Description

ASCC1 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: ASCC1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8N9N2
• Gene Symbols: Ascc1
• Immunogen: Full length human recombinant protein of ASCC1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI6G5
• Conjugate: Unconjugated
• Gene: Ascc1
• Gene Alias: 1810015P09Rik; activating signal cointegrator 1 complex subuni 1-like protein; activating signal cointegrator 1 complex subunit 1; AI550520; Asc-1; ASC-1 complex subunit p50; ASC1p50; Ascc1; CGI-18; p50; SMABF2; Trip4 complex subunit p50
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51008
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid