ASCC1 Mouse anti-Human, Clone: OTI6G5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF503721

Catalog No. 50-166-2339

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: ASCC1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ASCC1
• Gene Alias: ASC1p50, CGI-18, SMABF2, p50
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51008
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6G5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8N9N2
• Gene Symbols: ASCC1
• Immunogen: Full length human recombit protein of human ASCC1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1