Invitrogen™ ASCC1 Polyclonal Antibody

Catalog No.	Quantity
PA550355	100 μL

Catalog No. PA550355 Supplier Invitrogen™ Supplier No. PA550355

Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ASCC1 protein.

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: ASCC1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: Ascc1
• Gene Accession No.: Q8N9N2
• Gene Alias: 1810015P09Rik; activating signal cointegrator 1 complex subuni 1-like protein; activating signal cointegrator 1 complex subunit 1; AI550520; Asc-1; ASC-1 complex subunit p50; ASC1p50; Ascc1; CGI-18; p50; SMABF2; Trip4 complex subunit p50
• Gene Symbols: Ascc1
• Host Species: Rabbit
• Immunogen: Fusion protein corresponding to residues near the C terminal of human activating signal cointegrator 1 complex subunit 1.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51008
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG