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Invitrogen™ ASCC2 Polyclonal Antibody
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Catalog No. PIPA530849
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100 μL
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Catalog No. Quantity
PIPA530849 100 μL
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Catalog No. PIPA530849 Supplier Invitrogen™ Supplier No. PA530849
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (81%), Rat (82%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASCC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene ASCC2
Gene Accession No. Q9H1I8
Gene Alias 1700011I11Rik; 2610034L15Rik; activating signal cointegrator 1 complex subunit 2; AI482016; ASC-1 complex subunit P100; Asc1p100; ASCC2; AW046480; p100; RGD1561422; trip4 complex subunit p100
Gene Symbols ASCC2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ASCC2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84164
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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